V-set and immunoglobulin domain containing 4

VSIG4
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	2ICC, 2ICE, 2ICF
Identifiers
Aliases	VSIG4, CRIg, Z39IG, V-set and immunoglobulin domain containing 4
External IDs	OMIM: 300353; MGI: 2679720; HomoloGene: 48515; GeneCards: VSIG4; OMA:VSIG4 - orthologs
Gene location (Human)
Chr.	X chromosome (human)
End	66,040,125 bp
Gene location (Mouse)
Chr.	X chromosome (mouse)
End	95,337,044 bp
RNA expression pattern
	Top expressed in
	right lung; ; lower lobe of lung; ; gastric mucosa; ; right coronary artery; ; right adrenal cortex; ; synovial membrane; ; upper lobe of lung; ; upper lobe of left lung; ; synovial joint; ; visceral pleura;
	Top expressed in
	stroma of bone marrow; ; ankle; ; liver; ; left lobe of liver; ; myocardium of ventricle; ; tibiofemoral joint; ; granulocyte; ; muscle of thigh; ; aorta; ; skin of external ear;
	More reference expression data
	n/a
Gene ontology
Molecular function	protein binding; complement component C3b binding;
Cellular component	integral component of membrane; membrane; protein-containing complex;
Biological process	innate immune response; complement activation, alternative pathway; immune system process; negative regulation of interleukin-2 production; negative regulation of T cell proliferation; negative regulation of macrophage activation; negative regulation of complement activation, alternative pathway;
	Sources:Amigo / QuickGO
Orthologs
	11326
	278180
	ENSG00000155659
	ENSMUSG00000044206
	Q9Y279
	F6TUL9
	NM_007268; NM_001100431; NM_001184830; NM_001184831; NM_001257403
	NM_177789
	NP_001093901; NP_001171759; NP_001171760; NP_001244332; NP_009199
	NP_808457
	Wikidata
View/Edit Human	View/Edit Mouse

V-set and immunoglobulin domain containing 4 is a protein that in humans is encoded by the VSIG4 gene.