Visinin-like protein 1

VSNL1
Identifiers
Aliases	VSNL1, HLP3, HPCAL3, HUVISL1, VILIP, VILIP-1, visinin like 1
External IDs	OMIM: 600817; MGI: 1349453; HomoloGene: 2542; GeneCards: VSNL1; OMA:VSNL1 - orthologs
Gene location (Human)
Chr.	Chromosome 2 (human)
End	17,657,018 bp
Gene location (Mouse)
Chr.	Chromosome 12 (mouse)
End	11,486,614 bp
RNA expression pattern
	Top expressed in
	middle temporal gyrus; ; Brodmann area 23; ; orbitofrontal cortex; ; Pons; ; superior frontal gyrus; ; endothelial cell; ; Brodmann area 10; ; Brodmann area 46; ; occipital lobe; ; primary visual cortex;
	Top expressed in
	lateral septal nucleus; ; primary motor cortex; ; superior colliculus; ; pontine nuclei; ; ventral tegmental area; ; mammillary body; ; medial dorsal nucleus; ; central gray substance of midbrain; ; lobe of cerebellum; ; lateral hypothalamus;
	More reference expression data
	; ;
	More reference expression data
Gene ontology
Molecular function	calcium ion binding; protein binding; metal ion binding;
Cellular component	cytosol; membrane;
Biological process	positive regulation of exocytosis; positive regulation of insulin secretion involved in cellular response to glucose stimulus; negative regulation of insulin secretion;
	Sources:Amigo / QuickGO
Orthologs
	7447
	26950
	ENSG00000163032
	ENSMUSG00000054459
	P62760
	P62761
	NM_003385
	NM_012038; NM_001378929
	NP_003376; NP_001353732; NP_001353733; NP_001353734; NP_001353735
	NP_036168; NP_001365858
	Wikidata
View/Edit Human	View/Edit Mouse

Visinin-like protein 1 is a protein that in humans is encoded by the VSNL1 gene.

This gene is a member of the visinin/recoverin subfamily of neuronal calcium sensor proteins.

The encoded protein is strongly expressed in granule cells of the cerebellum where it associates with membranes in a calcium-dependent manner and modulates intracellular signaling pathways of the central nervous system by directly or indirectly regulating the activity of adenylyl cyclase. Alternatively spliced transcript variants have been observed, but their full-length nature has not been determined.