Variegate porphyria

Variegate porphyria
Other namesMixed hepatic porphyria, Mixed porphyria, South African genetic porphyria,:525 and South African porphyria.
Protoporphyrinogen IX
SpecialtyEndocrinology 
Symptomsskin problems, Enzyme difficiency.
Causesgenetic mutations.
Treatmentliver transplants.

Variegate porphyria, also known by several other names, is an autosomal dominant porphyria that can have acute (severe but usually not long-lasting) symptoms along with symptoms that affect the skin. The disorder results from low levels of the enzyme responsible for the seventh step in heme production. Heme is a vital molecule for all of the body's organs. It is a component of hemoglobin, the molecule that carries oxygen in the blood.