Parinaud's syndrome

Parinaud's syndrome
Other namesDorsal midbrain syndrome, vertical gaze palsy, upward gaze palzy, sunset sign, setting-sun sign, sun-setting sign, sunsetting sign, sunset eye sign, setting-sun phenomenon
SpecialtyNeurology 

Parinaud's syndrome is a constellation of neurological signs indicating injury to the dorsal midbrain. More specifically, compression of the vertical gaze center at the rostral interstitial nucleus of medial longitudinal fasciculus (riMLF).

It is a group of abnormalities of eye movement and pupil dysfunction and is named for Henri Parinaud (1844–1905), considered to be the father of French ophthalmology.

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