WASF1

WASF1
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	3P8C, 4N78
Identifiers
Aliases	WASF1, SCAR1, WAVE, WAVE1, WAS protein family member 1, WASP family member 1, NEDALVS
External IDs	OMIM: 605035; MGI: 1890563; HomoloGene: 2920; GeneCards: WASF1; OMA:WASF1 - orthologs
Gene location (Human)
Chr.	Chromosome 6 (human)
End	110,180,004 bp
Gene location (Mouse)
Chr.	Chromosome 10 (mouse)
End	40,814,566 bp
RNA expression pattern
	Top expressed in
	Region I of hippocampus proper; ; Brodmann area 23; ; orbitofrontal cortex; ; superior frontal gyrus; ; postcentral gyrus; ; entorhinal cortex; ; primary visual cortex; ; middle temporal gyrus; ; prefrontal cortex; ; Brodmann area 9;
	Top expressed in
	piriform cortex; ; olfactory tubercle; ; subiculum; ; subdivision of hippocampus; ; hippocampus proper; ; Region I of hippocampus proper; ; temporal lobe; ; dentate gyrus; ; Amygdala; ; nucleus accumbens;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	actin binding; protein binding; protein kinase A binding; protein-containing complex binding;
Cellular component	cytoplasm; mitochondrial outer membrane; cell junction; synapse; cytoskeleton; mitochondrion; SCAR complex; lamellipodium; focal adhesion; actin cytoskeleton; protein-containing complex; dendrite cytoplasm; postsynapse;
Biological process	actin filament polymerization; Rac protein signal transduction; positive regulation of Arp2/3 complex-mediated actin nucleation; lamellipodium morphogenesis; actin cytoskeleton organization; neuron projection development; positive regulation of neurotrophin TRK receptor signaling pathway; dendrite extension; receptor-mediated endocytosis; cellular response to brain-derived neurotrophic factor stimulus; protein-containing complex assembly; modification of postsynaptic actin cytoskeleton; dendritic transport of mitochondrion;
	Sources:Amigo / QuickGO
Orthologs
	8936
	83767
	ENSG00000112290
	ENSMUSG00000019831
	Q92558
	Q8R5H6
	NM_001024934; NM_001024935; NM_001024936; NM_003931
	NM_031877; NM_001379453; NM_001379454
	NP_001020105; NP_001020106; NP_001020107; NP_003922
	NP_114083; NP_001366382; NP_001366383
	Wikidata
View/Edit Human	View/Edit Mouse

Wiskott–Aldrich syndrome protein family member 1, also known as WASP-family verprolin homologous protein 1 (WAVE1), is a protein that in humans is encoded by the WASF1 gene.