WDR3

WDR3
Identifiers
Aliases	WDR3, DIP2, UTP12, WD repeat domain 3
External IDs	OMIM: 604737; MGI: 2443143; HomoloGene: 4937; GeneCards: WDR3; OMA:WDR3 - orthologs
Gene location (Human)
Chr.	Chromosome 1 (human)
End	117,966,543 bp
Gene location (Mouse)
Chr.	Chromosome 3 (mouse)
End	100,069,723 bp
RNA expression pattern
	Top expressed in
	gingival epithelium; ; pancreatic ductal cell; ; buccal mucosa cell; ; parietal pleura; ; germinal epithelium; ; islet of Langerhans; ; visceral pleura; ; Epithelium of choroid plexus; ; epithelium of nasopharynx; ; hair follicle;
	Top expressed in
	primitive streak; ; medullary collecting duct; ; hand; ; condyle; ; epiblast; ; fossa; ; superior cervical ganglion; ; abdominal wall; ; renal corpuscle; ; hair follicle;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	snoRNA binding; RNA binding;
Cellular component	Pwp2p-containing subcomplex of 90S preribosome; small-subunit processome; nuclear membrane; nucleolus; nucleoplasm; nucleus;
Biological process	rRNA processing; maturation of SSU-rRNA;
	Sources:Amigo / QuickGO
Orthologs
	10885
	269470
	ENSG00000065183
	ENSMUSG00000033285
	Q9UNX4
	Q8BHB4
	NM_006784
	NM_175552; NM_001355657
	NP_006775
	NP_780761; NP_001342586
	Wikidata
View/Edit Human	View/Edit Mouse

WD repeat-containing protein 3 is a protein that in humans is encoded by the WDR3 gene.

This gene encodes a nuclear protein containing 10 WD repeats. WD repeats are approximately 30- to 40-amino acid domains containing several conserved residues, which usually include a trp-asp at the C-terminal end. Proteins belonging to the WD repeat family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation.