WDR88

WDR88
Identifiers
AliasesWDR88, PQWD, WD repeat domain 88
External IDsMGI: 2686275; HomoloGene: 27838; GeneCards: WDR88; OMA:WDR88 - orthologs
Orthologs
SpeciesHumanMouse
Entrez

126248

384605

Ensembl

ENSG00000166359

ENSMUSG00000118454

UniProt

Q6ZMY6

n/a

RefSeq (mRNA)

NM_173479

NM_001370886

RefSeq (protein)

NP_775750

n/a

Location (UCSC)Chr 19: 33.13 – 33.18 MbChr 7: 34.94 – 34.97 Mb
PubMed search
Wikidata
View/Edit HumanView/Edit Mouse

WDR88 (WD repeat containing protein 88) is a protein, which in humans, is encoded by the gene WDR88. It consists of seven WD40 repeats, which form a seven-bladed beta-propeller. Mutations within the WDR88 gene are associated with a variety of cancers, as well as schizophrenia and fungal infections.

The protein structure of WDR88 is characterized by the presence of seven WD40 repeats, which are short structural motifs of approximately 40 amino acids that often terminate in a tryptophan-aspartic acid (WD) dipeptide. These repeats typically form a beta-propeller structure, suggesting a potential role in protein-protein interactions.