Wee1
| Wee1 | |||||||
|---|---|---|---|---|---|---|---|
Crystal structure of human Wee1 | |||||||
| Identifiers | |||||||
| Symbol | Mitosis inhibitor protein kinase Wee1 | ||||||
| Alt. symbols | wee1 dual specificity protein kinase Wee1 | ||||||
| NCBI gene | 2539123 | ||||||
| UniProt | P07527 | ||||||
| Other data | |||||||
| EC number | 2.7.11.1 | ||||||
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Wee1 is a nuclear kinase belonging to the Ser/Thr family of protein kinases in the fission yeast Schizosaccharomyces pombe (S. pombe). Wee1 has a molecular mass of 96 kDa and is a key regulator of cell cycle progression.
It influences cell size by inhibiting the entry into mitosis, through inhibiting Cdk1. Wee1 has homologues in many other organisms, including mammals.