WIF1

WIF1
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	2D3J, 2YGN, 2YGO, 2YGP, 2YGQ
Identifiers
Aliases	WIF1, WIF-1, WNT inhibitory factor 1
External IDs	OMIM: 605186; MGI: 1344332; HomoloGene: 31430; GeneCards: WIF1; OMA:WIF1 - orthologs
Gene location (Human)
Chr.	Chromosome 12 (human)
End	65,121,305 bp
Gene location (Mouse)
Chr.	Chromosome 10 (mouse)
End	120,936,555 bp
RNA expression pattern
	Top expressed in
	lower lobe of lung; ; periodontal fiber; ; tibia; ; parotid gland; ; caudate nucleus; ; putamen; ; corpus epididymis; ; tail of epididymis; ; nucleus accumbens; ; trabecular bone;
	Top expressed in
	molar; ; skin of external ear; ; dermis; ; body of femur; ; seminal vesicula; ; intercostal muscle; ; trachea; ; ankle; ; calvaria; ; conjunctival fornix;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	Wnt-protein binding; protein binding; signaling receptor binding;
Cellular component	extracellular region; cell surface;
Biological process	multicellular organism development; negative regulation of Wnt signaling pathway; Wnt signaling pathway; signal transduction; positive regulation of fat cell differentiation; anatomical structure development;
	Sources:Amigo / QuickGO
Orthologs
	11197
	24117
	ENSG00000156076
	ENSMUSG00000020218
	Q9Y5W5
	Q9WUA1
	NM_007191
	NM_011915
	NP_009122
	NP_036045
	Wikidata
View/Edit Human	View/Edit Mouse

Wnt inhibitory factor 1 is a protein that in humans is encoded by the WIF1 gene. WIF1 is a lipid-binding protein that binds to Wnt proteins and prevents them from triggering signalling.