WNT1-inducible-signaling pathway protein 3

CCN6
Identifiers
Aliases	CCN6, LIBC, PPAC, PPD, WISP-3, WNT1 inducible signaling pathway protein 3, WISP3, cellular communication network factor 6, PPRD
External IDs	OMIM: 603400; MGI: 2685581; HomoloGene: 77038; GeneCards: CCN6; OMA:CCN6 - orthologs
Gene location (Human)
Chr.	Chromosome 6 (human)
End	112,069,686 bp
Gene location (Mouse)
Chr.	Chromosome 10 (mouse)
End	39,163,794 bp
RNA expression pattern
	Top expressed in
	tibia; ; testicle; ; cartilage tissue; ; sperm; ; corpus epididymis; ; cerebellar hemisphere; ; right hemisphere of cerebellum; ; right uterine tube; ; right testis; ; skin of leg;
	Top expressed in
	secondary oocyte; ; primary oocyte; ; zygote; ; neural layer of retina; ; thymus; ; embryo; ; embryo; ; bone marrow; ; granulocyte; ; lens;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	insulin-like growth factor binding; growth factor activity; integrin binding; heparin binding;
Cellular component	extracellular region; extracellular space; endoplasmic reticulum; extracellular matrix; mitochondrion;
Biological process	cell-cell signaling; regulation of cell growth; signal transduction; cell adhesion; negative regulation of cell death; regulation of signaling receptor activity; regulation of mitochondrial membrane potential; regulation of reactive oxygen species biosynthetic process;
	Sources:Amigo / QuickGO
Orthologs
	8838
	327743
	ENSG00000112761
	ENSMUSG00000062074
	O95389
	D3Z5L9
	NM_003880; NM_130396; NM_198239
	NM_001127376
	NP_003871; NP_937882
	NP_001120848
	Wikidata
View/Edit Human	View/Edit Mouse

WNT1-inducible-signaling pathway protein 3 (WISP3, also named CCN6) is a matricellular protein that in humans is encoded by the WISP3 gene.