WNT16

WNT16
Identifiers
Aliases	WNT16, Wnt family member 16
External IDs	OMIM: 606267; MGI: 2136018; HomoloGene: 62175; GeneCards: WNT16; OMA:WNT16 - orthologs
Gene location (Human)
Chr.	Chromosome 7 (human)
End	121,341,104 bp
Gene location (Mouse)
Chr.	Chromosome 6 (mouse)
End	22,298,521 bp
RNA expression pattern
	Top expressed in
	testicle; ; skin of hip; ; skin of thigh; ; skin of abdomen; ; Achilles tendon; ; granulocyte; ; vagina; ; tail of epididymis; ; germinal epithelium; ; endothelial cell;
	Top expressed in
	female urethra; ; epithelium of female urethra; ; ascending aorta; ; iris; ; semi-lunar valve; ; aortic valve; ; lamina propria of urethra; ; hand joint; ; ciliary body; ; prostatic epithelium;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	signaling receptor binding; frizzled binding;
Cellular component	cytoplasm; extracellular region; extracellular space;
Biological process	multicellular organism development; optic cup formation involved in camera-type eye development; positive regulation of phosphatidylinositol 3-kinase signaling; keratinocyte proliferation; cell fate commitment; positive regulation of gene expression; positive regulation of JNK cascade; bone remodeling; negative regulation of cell death; neuron differentiation; oxidative stress-induced premature senescence; keratinocyte differentiation; cardiac epithelial to mesenchymal transition; replicative senescence; Wnt signaling pathway;
	Sources:Amigo / QuickGO
Orthologs
	51384
	93735
	ENSG00000002745
	ENSMUSG00000029671
	Q9UBV4
	Q9QYS1
	NM_057168; NM_016087
	NM_053116
	NP_057171; NP_476509
	NP_444346
	Wikidata
View/Edit Human	View/Edit Mouse

Protein Wnt-16 is a protein that in humans is encoded by the WNT16 gene. It has been proposed that stimulation of WNT16 expression in nearby normal cells is responsible for the development of chemotherapy-resistance in cancer cells.