WNT2B

WNT2B
Identifiers
Aliases	WNT2B, WNT13, Wnt family member 2B
External IDs	OMIM: 601968; MGI: 1261834; HomoloGene: 22526; GeneCards: WNT2B; OMA:WNT2B - orthologs
Gene location (Human)
Chr.	Chromosome 1 (human)
End	112,530,165 bp
Gene location (Mouse)
Chr.	Chromosome 3 (mouse)
End	104,869,237 bp
RNA expression pattern
	Top expressed in
	germinal epithelium; ; buccal mucosa cell; ; parietal pleura; ; gonad; ; skin of hip; ; optic nerve; ; skin of thigh; ; epithelium of colon; ; right ovary; ; left ovary;
	Top expressed in
	epithelium of female urethra; ; muscle layer of urethra; ; pretectal area; ; muscle layer of ejaculatory duct; ; lamina propria of urethra; ; vagina; ; anterior lobe of prostate; ; lamina propria of vagina; ; pelvic part of vagina; ; muscle layer of seminal vesicle;
	More reference expression data
	; ;
	More reference expression data
Gene ontology
Molecular function	frizzled binding; signaling receptor binding;
Cellular component	extracellular region; extracellular space; intracellular membrane-bounded organelle; collagen-containing extracellular matrix;
Biological process	cell fate commitment; positive regulation of branching involved in ureteric bud morphogenesis; male gonad development; chondrocyte differentiation; positive regulation of canonical Wnt signaling pathway; iris morphogenesis; cornea development in camera-type eye; cellular response to starvation; hematopoietic stem cell proliferation; lung induction; multicellular organism development; forebrain regionalization; lens development in camera-type eye; neuron differentiation; mesenchymal-epithelial cell signaling; canonical Wnt signaling pathway; Wnt signaling pathway;
	Sources:Amigo / QuickGO
Orthologs
	7482
	22414
	ENSG00000134245
	ENSMUSG00000027840
	Q93097
	O70283
	NM_024494; NM_001291880; NM_004185
	NM_009520
	NP_001278809; NP_004176; NP_078613
	NP_033546
	Wikidata
View/Edit Human	View/Edit Mouse

Protein Wnt-2b (formerly Wnt13) is a protein that in humans is encoded by the WNT2B gene.

This gene encodes a member of the wingless-type MMTV integration site (WNT) family of highly conserved, secreted signaling factors. WNT family members function in a variety of developmental processes including regulation of cell growth and differentiation and are characterized by a WNT-core domain. This gene may play a role in human development as well as human carcinogenesis. This gene produces two alternative transcript variants.