WNT7B

WNT7B
Identifiers
Aliases	WNT7B, Wnt family member 7B
External IDs	OMIM: 601967; MGI: 98962; HomoloGene: 22531; GeneCards: WNT7B; OMA:WNT7B - orthologs
Gene location (Human)
Chr.	Chromosome 22 (human)
End	45,977,162 bp
Gene location (Mouse)
Chr.	Chromosome 15 (mouse)
End	85,466,674 bp
RNA expression pattern
	Top expressed in
	vena cava; ; buccal mucosa cell; ; olfactory zone of nasal mucosa; ; mucosa of pharynx; ; skin of abdomen; ; nipple; ; skin of leg; ; renal medulla; ; mucosa of esophagus; ; Amygdala;
	Top expressed in
	epithelium of male urethra; ; epithelium of lens; ; esophagus; ; lumbar subsegment of spinal cord; ; set of lens fibers; ; medullary collecting duct; ; subiculum; ; ganglionic eminence; ; transitional epithelium of urinary bladder; ; dentate gyrus of hippocampal formation granule cell;
	More reference expression data
	n/a
Gene ontology
Molecular function	frizzled binding; signaling receptor binding; receptor ligand activity;
Cellular component	endocytic vesicle membrane; endoplasmic reticulum lumen; extracellular region; Golgi lumen; extracellular exosome; plasma membrane; cytoplasm; extracellular space;
Biological process	cellular response to retinoic acid; cell fate commitment; renal inner medulla development; lung morphogenesis; mammary gland epithelium development; stem cell proliferation; embryonic organ development; lung development; renal outer medulla development; embryonic placenta morphogenesis; synapse organization; metanephric epithelium development; in utero embryonic development; trachea cartilage morphogenesis; chorio-allantoic fusion; multicellular organism development; developmental growth involved in morphogenesis; forebrain regionalization; positive regulation of osteoblast differentiation; cell metabolism; metanephric loop of Henle development; neuron differentiation; central nervous system vasculogenesis; fibroblast proliferation; lobar bronchus development; metanephros morphogenesis; inner medullary collecting duct development; metanephric collecting duct development; establishment or maintenance of polarity of embryonic epithelium; lung epithelium development; outer medullary collecting duct development; oxygen homeostasis; lens fiber cell development; homeostatic process; regulation of cell projection size; response to glucocorticoid; neuron projection morphogenesis; Wnt signaling pathway; neuron projection development; positive regulation of JNK cascade; canonical Wnt signaling pathway; regulation of signaling receptor activity;
	Sources:Amigo / QuickGO
Orthologs
	7477
	22422
	ENSG00000188064
	ENSMUSG00000022382
	P56706
	P28047
	NM_058238
	NM_001163633; NM_001163634; NM_009528
	NP_478679
	NP_001157105; NP_001157106; NP_033554
	Wikidata
View/Edit Human	View/Edit Mouse

Wnt7b is a signaling protein that plays a crucial role for many developmental processes including placental, lung, eye, dendrite, and bone formation along with kidney development. The primary role of Wnt7b is to establish the cortico-medullary axis of epithelial organization.

Protein Wnt-7b is a protein that in humans is encoded by the WNT7B gene.