Orangeburg-Wilkinson High School
| Orangeburg-Wilkinson High School | |
|---|---|
| Address | |
601 Bruin Pkwy 29118 United States  | |
| Coordinates | 33°31′26″N 80°50′11″W / 33.5239°N 80.8364°W | 
| Information | |
| Type | Public | 
| Established | 1971 | 
| School district | Orangeburg County School District | 
| Principal | Rahim El-Amin | 
| Grades | 9–12 | 
| Enrollment | 1,050 (2023–2024) | 
| Color(s) | Maroon, orange, and white  | 
| Mascot | Bruin | 
| Website | www | 
Orangeburg-Wilkinson High School is located in Orangeburg, South Carolina.
It is a part of the Orangeburg County School District. It is home to the Mighty Bruins/Bruinettes and also an International Baccalaureate World School.