XPA

XPA
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	1D4U, 1XPA, 2JNW
Identifiers
Aliases	XPA, XP1, XPAC, xeroderma pigmentosum, complementation group A, DNA damage recognition and repair factor
External IDs	OMIM: 611153; MGI: 99135; HomoloGene: 37298; GeneCards: XPA; OMA:XPA - orthologs
Gene location (Mouse)
Chr.	Chromosome 4 (mouse)
End	46,196,311 bp
RNA expression pattern
	n/a
	Top expressed in
	granulocyte; ; genital tubercle; ; neural layer of retina; ; ventricular zone; ; right kidney; ; ganglionic eminence; ; muscle of thigh; ; embryo; ; tail of embryo; ; proximal tubule;
	More reference expression data
Gene ontology
Molecular function	metal ion binding; protein domain specific binding; protein homodimerization activity; DNA binding; protein binding; damaged DNA binding;
Cellular component	intercellular bridge; DNA replication factor A complex; nucleotide-excision repair factor 1 complex; nucleus; nucleoplasm; cytoplasm;
Biological process	nucleotide-excision repair, DNA incision; intrinsic apoptotic signaling pathway in response to DNA damage; transcription-coupled nucleotide-excision repair; response to oxidative stress; cellular response to DNA damage stimulus; response to auditory stimulus; multicellular organism growth; global genome nucleotide-excision repair; response to toxic substance; response to UV; nucleotide-excision repair, preincision complex assembly; nucleotide-excision repair; nucleotide-excision repair, DNA incision, 5'-to lesion; nucleotide-excision repair involved in interstrand cross-link repair; UV-damage excision repair; base-excision repair; nucleotide-excision repair, preincision complex stabilization; nucleotide-excision repair, DNA damage recognition; DNA repair; UV protection; protein localization to nucleus; regulation of autophagy; nucleotide-excision repair, DNA duplex unwinding; nucleotide-excision repair, DNA incision, 3'-to lesion;
	Sources:Amigo / QuickGO
Orthologs
	7507
	22590
	ENSG00000136936
	ENSMUSG00000028329
	P23025
	Q64267
	NM_000380
	NM_011728
	NP_000371; NP_001341904
	NP_035858
	Wikidata
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DNA repair protein complementing XP-A cells is a protein that in humans is encoded by the XPA gene.