XPNPEP2

XPNPEP2
Identifiers
AliasesXPNPEP2, AEACEI, APP2, X-prolyl aminopeptidase (aminopeptidase P) 2, membrane-bound, X-prolyl aminopeptidase 2
External IDsOMIM: 300145; MGI: 2180001; HomoloGene: 37766; GeneCards: XPNPEP2; OMA:XPNPEP2 - orthologs
Orthologs
SpeciesHumanMouse
Entrez

7512

170745

Ensembl

ENSG00000122121

ENSMUSG00000037005

UniProt

O43895

B1AVD1

RefSeq (mRNA)

NM_003399

NM_001289729
NM_133213

RefSeq (protein)

NP_003390

NP_001276658
NP_573476

Location (UCSC)Chr X: 129.74 – 129.77 MbChr X: 47.2 – 47.23 Mb
PubMed search
Wikidata
View/Edit HumanView/Edit Mouse

Xaa-Pro aminopeptidase 2 is an enzyme that in humans is encoded by the XPNPEP2 gene.

Aminopeptidase P is a hydrolase specific for N-terminal imido bonds, which are common to several collagen degradation products, neuropeptides, vasoactive peptides, and cytokines. Structurally, the enzyme is a member of the 'pita bread fold' family and occurs in mammalian tissues in both soluble and GPI-anchored membrane-bound forms. A membrane-bound and soluble form of this enzyme have been identified as products of two separate genes.