XPO6

XPO6
Identifiers
Aliases	XPO6, EXP6, RANBP20, exportin 6
External IDs	OMIM: 608411; MGI: 2429950; HomoloGene: 12544; GeneCards: XPO6; OMA:XPO6 - orthologs
Gene location (Human)
Chr.	Chromosome 16 (human)
End	28,211,965 bp
Gene location (Mouse)
Chr.	Chromosome 7 (mouse)
End	125,799,673 bp
RNA expression pattern
	Top expressed in
	blood; ; granulocyte; ; left testis; ; right testis; ; spleen; ; epithelium of colon; ; C1 segment; ; tibial nerve; ; upper lobe of left lung; ; right frontal lobe;
	Top expressed in
	tail of embryo; ; genital tubercle; ; granulocyte; ; spermatocyte; ; dentate gyrus of hippocampal formation granule cell; ; ventricular zone; ; spermatid; ; yolk sac; ; epiblast; ; seminiferous tubule;
	More reference expression data
	; ; ; ;
	More reference expression data
Gene ontology
Molecular function	protein binding; nuclear export signal receptor activity;
Cellular component	plasma membrane; nucleolus; nucleus; cytoplasm; cytosol; protein-containing complex;
Biological process	protein transport; intracellular protein transport; protein export from nucleus;
	Sources:Amigo / QuickGO
Orthologs
	23214
	74204
	ENSG00000169180
	ENSMUSG00000000131
	Q96QU8
	Q924Z6
	NM_001270940; NM_015171
	NM_028816; NM_001311143
	NP_001257869; NP_055986
	NP_001298072; NP_083092
	Wikidata
View/Edit Human	View/Edit Mouse

Exportin-6 is a protein that in humans is encoded by the XPO6 gene.

Exportins, such as XPO6, recruit cargo in the nucleoplasm in the presence of Ran-GTP and form ternary export complexes. These complexes are transported through nuclear pore complexes to the cytoplasm, where GTP is hydrolyzed and the export complex is disassembled.