XPOT

XPOT
Identifiers
Aliases	XPOT, XPO3, exportin for tRNA
External IDs	OMIM: 603180; MGI: 1920442; HomoloGene: 38291; GeneCards: XPOT; OMA:XPOT - orthologs
Gene location (Human)
Chr.	Chromosome 12 (human)
End	64,451,125 bp
Gene location (Mouse)
Chr.	Chromosome 10 (mouse)
End	121,462,237 bp
RNA expression pattern
	Top expressed in
	stromal cell of endometrium; ; endothelial cell; ; Brodmann area 23; ; islet of Langerhans; ; Achilles tendon; ; bone marrow cells; ; ventricular zone; ; body of pancreas; ; middle temporal gyrus; ; ganglionic eminence;
	Top expressed in
	ureter; ; lacrimal gland; ; calvaria; ; renal corpuscle; ; fossa; ; condyle; ; parotid gland; ; hair follicle; ; substantia nigra; ; medullary collecting duct;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	tRNA binding; RNA binding;
Cellular component	cytoplasm; nuclear matrix; nuclear pore; nucleus; nucleoplasm; cytosol;
Biological process	intracellular protein transport; tRNA re-export from nucleus; tRNA export from nucleus;
	Sources:Amigo / QuickGO
Orthologs
	11260
	73192
	ENSG00000184575
	ENSMUSG00000034667
	O43592
	Q9CRT8
	NM_007235
	NM_001081056; NM_001359618; NM_001401044; NM_001401045
	NP_009166
	NP_001074525; NP_001346547; NP_001387973; NP_001387974
	Wikidata
View/Edit Human	View/Edit Mouse

Exportin-T is a protein that in humans is encoded by the XPOT gene.

This gene encodes a protein belonging to the RAN-GTPase exportin family that mediates export of tRNA from the nucleus to the cytoplasm. Translocation of tRNA to the cytoplasm occurs once exportin has bound both tRNA and GTP-bound RAN.