YTHDC1

YTHDC1
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	2YUD, 4R3H, 4R3I
Identifiers
Aliases	YTHDC1, YT521, YT521-B, YTH domain containing 1
External IDs	OMIM: 617283; MGI: 2443713; HomoloGene: 15796; GeneCards: YTHDC1; OMA:YTHDC1 - orthologs
Gene location (Human)
Chr.	Chromosome 4 (human)
End	68,350,090 bp
Gene location (Mouse)
Chr.	Chromosome 5 (mouse)
End	86,984,518 bp
RNA expression pattern
	Top expressed in
	Achilles tendon; ; corpus callosum; ; sural nerve; ; left ovary; ; bone marrow; ; endometrium; ; ventricular zone; ; right ovary; ; right lung; ; vagina;
	Top expressed in
	medullary collecting duct; ; conjunctival fornix; ; renal corpuscle; ; cumulus cell; ; ureter; ; ciliary body; ; pineal gland; ; vestibular membrane of cochlear duct; ; Rostral migratory stream; ; Paneth cell;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	protein binding; RNA binding; N6-methyladenosine-containing RNA binding;
Cellular component	nucleus; nuclear speck; plasma membrane; nucleoplasm;
Biological process	mRNA processing; mRNA splice site selection; RNA splicing; regulation of mRNA splicing, via spliceosome; mRNA export from nucleus; dosage compensation by inactivation of X chromosome; posttranscriptional regulation of gene expression;
	Sources:Amigo / QuickGO
Orthologs
	91746
	231386
	ENSG00000275272; ENSG00000083896
	ENSMUSG00000035851
	Q96MU7
	E9Q5K9
	NM_001031732; NM_133370; NM_001330698
	NM_177680; NM_001347375; NM_001347376; NM_001359907; NM_001359908
	NP_001026902; NP_001317627; NP_588611
	NP_001334304; NP_001334305; NP_808348; NP_001346836; NP_001346837
	Wikidata
View/Edit Human	View/Edit Mouse

YTH domain-containing protein 1 is a protein that in humans is encoded by the YTHDC1 gene. YTHDC1 is a nuclear protein involved in splice site selection that localises to YT bodies; dynamic subnuclear compartments, which first appear at the beginning of S-phase in the cell cycle and disperse during mitosis.