YTH protein domain
| YTH protein domain | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| Symbol | YTH | ||||||||
| Pfam | PF04146 | ||||||||
| Pfam clan | CL0178 | ||||||||
| InterPro | IPR007275 | ||||||||
| |||||||||
In molecular biology, the protein domain YTH refers to a member of the YTH family that has been shown to selectively remove transcripts of meiosis-specific genes expressed in mitotic cells. They also play a role in the epitranscriptome as reader proteins for m6A.
This protein domain, the YTH-domain, is conserved across all eukaryotes and suggests that the conserved C-terminal region plays a critical role in relaying the cytosolic Ca-signals to the nucleus, thereby regulating gene expression.