YY1

YY1
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	1UBD, 1ZNM, 4C5I
Identifiers
Aliases	YY1, DELTA, INO80S, NF-E1, UCRBP, YIN-YANG-1, YY1 transcription factor, GADEVS
External IDs	OMIM: 600013; MGI: 99150; HomoloGene: 2556; GeneCards: YY1; OMA:YY1 - orthologs
Gene location (Human)
Chr.	Chromosome 14 (human)
End	100,282,788 bp
Gene location (Mouse)
Chr.	Chromosome 12 (mouse)
End	108,786,074 bp
RNA expression pattern
	Top expressed in
	ventricular zone; ; ganglionic eminence; ; endothelial cell; ; middle temporal gyrus; ; Brodmann area 23; ; rectum; ; monocyte; ; tonsil; ; sural nerve; ; skin of thigh;
	Top expressed in
	medullary collecting duct; ; primitive streak; ; ureter; ; renal corpuscle; ; Gonadal ridge; ; abdominal wall; ; left lung lobe; ; cumulus cell; ; human fetus; ; endocardial cushion;
	More reference expression data
	; ;
	More reference expression data
Gene ontology
Molecular function	DNA binding; transcription corepressor activity; transcription coactivator activity; zinc ion binding; metal ion binding; protein binding; four-way junction DNA binding; cis-regulatory region sequence-specific DNA binding; RNA binding; nucleic acid binding; SMAD binding; RNA polymerase II cis-regulatory region sequence-specific DNA binding; DNA-binding transcription repressor activity, RNA polymerase II-specific; DNA-binding transcription factor activity; sequence-specific DNA binding; DNA-binding transcription factor activity, RNA polymerase II-specific; histone deacetylase binding;
Cellular component	Ino80 complex; nuclear matrix; nucleus; nucleoplasm; transcription regulator complex; cytoplasm; PcG protein complex;
Biological process	cell differentiation; DNA recombination; regulation of transcription, DNA-templated; regulation of transcription by RNA polymerase II; cellular response to UV; negative regulation of gene expression; transcription, DNA-templated; cellular response to DNA damage stimulus; double-strand break repair via homologous recombination; spermatogenesis; DNA repair; protein deubiquitination; negative regulation of interferon-beta production; negative regulation of transcription by RNA polymerase II; RNA localization; anterior/posterior pattern specification; response to UV-C; positive regulation of gene expression; response to prostaglandin F; positive regulation of transcription by RNA polymerase II; camera-type eye morphogenesis; chromosome organization; cellular response to interleukin-1; negative regulation of pri-miRNA transcription by RNA polymerase II; negative regulation of cell growth involved in cardiac muscle cell development;
	Sources:Amigo / QuickGO
Orthologs
	7528
	22632
	ENSG00000100811
	ENSMUSG00000021264
	P25490
	Q00899
	NM_003403
	NM_009537
	NP_003394
	NP_033563
	Wikidata
View/Edit Human	View/Edit Mouse

YY1 (Yin Yang 1) is a transcriptional repressor protein in humans that is encoded by the YY1 gene.