Zinc finger and BTB domain-containing protein 16

ZBTB16
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	1BUO, 1CS3
Identifiers
Aliases	ZBTB16, PLZF, ZNF145, zinc finger and BTB domain containing 16
External IDs	OMIM: 176797; MGI: 103222; HomoloGene: 21214; GeneCards: ZBTB16; OMA:ZBTB16 - orthologs
Gene location (Human)
Chr.	Chromosome 11 (human)
End	114,256,765 bp
Gene location (Mouse)
Chr.	Chromosome 9 (mouse)
End	48,747,522 bp
RNA expression pattern
	Top expressed in
	skin of hip; ; Brodmann area 23; ; tibialis anterior muscle; ; Skeletal muscle tissue of rectus abdominis; ; pericardium; ; saphenous vein; ; skin of thigh; ; deltoid muscle; ; biceps brachii; ; Skeletal muscle tissue of biceps brachii;
	Top expressed in
	extensor digitorum longus muscle; ; plantaris muscle; ; digastric muscle; ; extraocular muscle; ; aortic valve; ; gastrula; ; muscle of thigh; ; ankle; ; thoracic diaphragm; ; soleus muscle;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	RNA polymerase II cis-regulatory region sequence-specific DNA binding; DNA binding; protein homodimerization activity; DNA-binding transcription factor activity; metal ion binding; DNA-binding transcription repressor activity, RNA polymerase II-specific; protein binding; identical protein binding; nucleic acid binding; double-stranded DNA binding; DNA-binding transcription factor activity, RNA polymerase II-specific; protein C-terminus binding; protein domain specific binding; sequence-specific DNA binding;
Cellular component	PML body; nuclear speck; nuclear body; plasma membrane; transcription repressor complex; nucleus; cytosol; protein-containing complex; nucleoplasm;
Biological process	embryonic hindlimb morphogenesis; forelimb morphogenesis; skeletal system development; myeloid cell differentiation; regulation of transcription, DNA-templated; embryonic pattern specification; embryonic digit morphogenesis; positive regulation of ossification; negative regulation of transcription by RNA polymerase II; hindlimb morphogenesis; transcription, DNA-templated; mesonephros development; positive regulation of transcription, DNA-templated; central nervous system development; cartilage development; male germ-line stem cell asymmetric division; positive regulation of cartilage development; protein ubiquitination; positive regulation of chondrocyte differentiation; positive regulation of apoptotic process; protein localization to nucleus; positive regulation of NK T cell differentiation; negative regulation of transcription, DNA-templated; positive regulation of fat cell differentiation; negative regulation of myeloid cell differentiation; anterior/posterior pattern specification; negative regulation of cell population proliferation; apoptotic process; post-translational protein modification; hemopoiesis; positive regulation of transcription by RNA polymerase II;
	Sources:Amigo / QuickGO
Orthologs
	7704
	235320
	ENSG00000109906
	ENSMUSG00000066687
	Q05516
	Q3UQ17
	NM_001018011; NM_006006; NM_001354750; NM_001354751; NM_001354752
	NM_001033324; NM_001364543
	NP_001018011; NP_005997; NP_001341679; NP_001341680; NP_001341681
	NP_001028496; NP_001351472
	Wikidata
View/Edit Human	View/Edit Mouse

Zinc finger and BTB domain-containing protein 16 is a protein that in humans is encoded by the ZBTB16 gene.