ZBTB7A

ZBTB7A
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	2IF5, 2NN2
Identifiers
Aliases	ZBTB7A, FBI-1, FBI1, LRF, ZBTB7, ZNF857A, pokemon, TIP21, zinc finger and BTB domain containing 7A, MNDLFH
External IDs	OMIM: 605878; MGI: 1335091; HomoloGene: 7820; GeneCards: ZBTB7A; OMA:ZBTB7A - orthologs
Gene location (Human)
Chr.	Chromosome 19 (human)
End	4,066,899 bp
Gene location (Mouse)
Chr.	Chromosome 10 (mouse)
End	80,988,829 bp
RNA expression pattern
	Top expressed in
	nipple; ; internal globus pallidus; ; middle temporal gyrus; ; pylorus; ; cerebellar vermis; ; Brodmann area 23; ; cardia; ; vulva; ; superior surface of tongue; ; ventral tegmental area;
	Top expressed in
	ascending aorta; ; aortic valve; ; inner renal medulla; ; superior frontal gyrus; ; glomerulus; ; lip; ; granulocyte; ; right kidney; ; esophagus; ; cerebellar cortex;
	More reference expression data
	; ; ; ;
	More reference expression data
Gene ontology
Molecular function	RNA polymerase II cis-regulatory region sequence-specific DNA binding; DNA binding; DNA-binding transcription repressor activity, RNA polymerase II-specific; protein binding; histone acetyltransferase binding; metal ion binding; nucleic acid binding; DNA-binding transcription factor activity, RNA polymerase II-specific; transcription corepressor binding; DNA-binding transcription factor activity; transcription corepressor activity; sequence-specific DNA binding; SMAD binding; androgen receptor binding;
Cellular component	nucleus; cytoplasm; NuRD complex; site of double-strand break; DNA-dependent protein kinase complex;
Biological process	multicellular organism development; cell differentiation; negative regulation of transcription, DNA-templated; regulation of transcription, DNA-templated; negative regulation of transcription by RNA polymerase II; transcription, DNA-templated; regulation of alternative mRNA splicing, via spliceosome; regulation of glycolytic process; chromatin organization; chromatin remodeling; cellular response to DNA damage stimulus; B cell differentiation; negative regulation of transforming growth factor beta receptor signaling pathway; protein localization to nucleus; regulation of apoptotic process; erythrocyte maturation; fat cell differentiation; negative regulation of Notch signaling pathway; regulation of DNA-binding transcription factor activity; positive regulation of NF-kappaB transcription factor activity; negative regulation of androgen receptor signaling pathway; double-strand break repair via classical nonhomologous end joining; regulation of transcription regulatory region DNA binding;
	Sources:Amigo / QuickGO
Orthologs
	51341
	16969
	ENSG00000178951
	ENSMUSG00000035011
	O95365
	O88939
	NM_015898; NM_001317990; NM_020224
	NM_010731
	NP_001304919; NP_056982
NP_034861; NP_001391790; NP_001391791; NP_001391792; NP_001391793;
	NP_001391794; NP_001391795; NP_001391796
	Wikidata
View/Edit Human	View/Edit Mouse

Zinc finger and BTB domain-containing protein 7A is a protein that in humans is encoded by the ZBTB7A gene.