Zinc finger homeobox 2

ZFHX2
Identifiers
Aliases	ZFHX2, ZFH-5, ZNF409, ZFH5, MARSIS, zinc finger homeobox 2
External IDs	OMIM: 617828; MGI: 2686934; HomoloGene: 52657; GeneCards: ZFHX2; OMA:ZFHX2 - orthologs
Gene location (Human)
Chr.	Chromosome 14 (human)
End	23,556,192 bp
Gene location (Mouse)
Chr.	Chromosome 14 (mouse)
End	55,329,781 bp
RNA expression pattern
	Top expressed in
	buccal mucosa cell; ; sperm; ; testicle; ; left testis; ; right testis; ; lateral nuclear group of thalamus; ; sural nerve; ; right hemisphere of cerebellum; ; right frontal lobe; ; primary visual cortex;
	Top expressed in
	superior frontal gyrus; ; neural layer of retina; ; primary visual cortex; ; ventricular zone; ; genital tubercle; ; urethra; ; cerebellar cortex; ; male urethra; ; neural tube; ; dentate gyrus of hippocampal formation granule cell;
	More reference expression data
	n/a
Gene ontology
Molecular function	sequence-specific DNA binding; DNA binding; zinc ion binding; metal ion binding; nucleic acid binding; DNA-binding transcription factor activity, RNA polymerase II-specific; RNA polymerase II cis-regulatory region sequence-specific DNA binding;
Cellular component	nucleus;
Biological process	adult behavior; regulation of transcription, DNA-templated; transcription, DNA-templated; regulation of transcription by RNA polymerase II; negative regulation of transcription by RNA polymerase II; positive regulation of transcription, DNA-templated; regulation of sensory perception of pain;
	Sources:Amigo / QuickGO
Orthologs
	85446
	239102
	ENSG00000136367
	ENSMUSG00000040721
	Q9C0A1
	Q2MHN3
	NM_033400
	NM_001039198
	NP_207646
	NP_001034287
	Wikidata
View/Edit Human	View/Edit Mouse

Zinc finger homeobox 2 is a protein that in humans is encoded by the ZFHX2 gene. It has been implicated in pain insensitivity.