ZHX3

ZHX3
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	2DA5, 2DN0
Identifiers
Aliases	ZHX3, TIX1, zinc fingers and homeoboxes 3
External IDs	OMIM: 609598; MGI: 2444772; HomoloGene: 9000; GeneCards: ZHX3; OMA:ZHX3 - orthologs
Gene location (Human)
Chr.	Chromosome 20 (human)
End	41,317,672 bp
Gene location (Mouse)
Chr.	Chromosome 2 (mouse)
End	160,714,918 bp
RNA expression pattern
	Top expressed in
	sural nerve; ; gastric mucosa; ; Achilles tendon; ; ventricular zone; ; corpus callosum; ; stromal cell of endometrium; ; popliteal artery; ; tibial arteries; ; internal globus pallidus; ; nucleus accumbens;
	Top expressed in
	otolith organ; ; utricle; ; zygote; ; secondary oocyte; ; spermatid; ; vestibular membrane of cochlear duct; ; lumbar subsegment of spinal cord; ; seminiferous tubule; ; ascending aorta; ; aortic valve;
	More reference expression data
	; ;
	More reference expression data
Gene ontology
Molecular function	DNA-binding transcription factor activity; DNA binding; protein binding; protein homodimerization activity; transcription corepressor activity; metal ion binding; protein heterodimerization activity; nucleic acid binding; RNA polymerase II transcription regulatory region sequence-specific DNA binding; DNA-binding transcription factor activity, RNA polymerase II-specific;
Cellular component	nucleus; nucleoplasm;
Biological process	cell differentiation; positive regulation of osteoblast differentiation; negative regulation of transcription, DNA-templated; regulation of transcription, DNA-templated; negative regulation of transcription by RNA polymerase II; transcription, DNA-templated;
	Sources:Amigo / QuickGO
Orthologs
	23051
	320799
	ENSG00000174306
	ENSMUSG00000035877
	Q9H4I2
	Q8C0Q2
	NM_015035
	NM_177263
	NP_055850
	NP_796237
	Wikidata
View/Edit Human	View/Edit Mouse

Zinc fingers and homeoboxes protein 3 is a protein that in humans is encoded by the ZHX3 gene.

This gene encodes a member of the zinc fingers and homeoboxes (ZHX) gene family. The encoded Protein contains two C2H2-type zinc fingers and five Homeodomains and forms a Dimer with itself or with Zinc fingers and homeoboxes family member 1. In the Nucleus, the dimerized protein interacts with the A subunit of the ubiquitous transcription factor nuclear factor-Y and may function as a transcriptional repressor.fx