ZIC2

ZIC2
Identifiers
Aliases	ZIC2, HPE5, Zic family member 2
External IDs	OMIM: 603073; MGI: 106679; HomoloGene: 5171; GeneCards: ZIC2; OMA:ZIC2 - orthologs
Gene location (Human)
Chr.	Chromosome 13 (human)
End	99,986,765 bp
Gene location (Mouse)
Chr.	Chromosome 14 (mouse)
End	122,717,264 bp
RNA expression pattern
	Top expressed in
	cerebellar cortex; ; cerebellar hemisphere; ; right hemisphere of cerebellum; ; Pons; ; cerebellar vermis; ; ventricular zone; ; trigeminal ganglion; ; endothelial cell; ; lateral nuclear group of thalamus; ; ganglionic eminence;
	Top expressed in
	cerebellar cortex; ; neural groove; ; neural fold; ; stria vascularis; ; epiblast; ; lumbar subsegment of spinal cord; ; ventricular zone; ; tail of embryo; ; urethra; ; male urethra;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	DNA-binding transcription factor activity; DNA binding; chromatin DNA binding; metal ion binding; nucleic acid binding; DNA-binding transcription factor activity, RNA polymerase II-specific; RNA polymerase II transcription regulatory region sequence-specific DNA binding; DNA-binding transcription activator activity, RNA polymerase II-specific;
Cellular component	cytoplasm; nucleus; nuclear body;
Biological process	positive regulation of transcription, DNA-templated; multicellular organism development; cell differentiation; brain development; positive regulation of DNA-binding transcription factor activity; negative regulation of transcription, DNA-templated; regulation of transcription, DNA-templated; transcription, DNA-templated; visual perception; nervous system development; regulation of transcription by RNA polymerase II; positive regulation of transcription by RNA polymerase II; central nervous system development;
	Sources:Amigo / QuickGO
Orthologs
	7546
	22772
	ENSG00000043355
	ENSMUSG00000061524
	O95409
	Q62520
	NM_007129
	NM_009574
	NP_009060
	NP_033600
	Wikidata
View/Edit Human	View/Edit Mouse

Zinc finger protein ZIC2 is a protein that in humans is encoded by the ZIC2 gene. ZIC2 is a member of the Zinc finger of the cerebellum (ZIC) protein family.