ZMYND8

ZMYND8
Available structures
PDB	Human UniProt search: PDBe RCSB
List of PDB id codes
	4COS
Identifiers
Aliases	ZMYND8, PRKCBP1, PRO2893, RACK7, zinc finger MYND-type containing 8
External IDs	OMIM: 615713; MGI: 1918025; HomoloGene: 32679; GeneCards: ZMYND8; OMA:ZMYND8 - orthologs
Gene location (Human)
Chr.	Chromosome 20 (human)
End	47,356,889 bp
Gene location (Mouse)
Chr.	Chromosome 2 (mouse)
End	165,740,936 bp
RNA expression pattern
	Top expressed in
	corpus epididymis; ; oocyte; ; caput epididymis; ; Pons; ; tail of epididymis; ; superior surface of tongue; ; superior vestibular nucleus; ; trigeminal ganglion; ; trabecular bone; ; pylorus;
	Top expressed in
	vestibular membrane of cochlear duct; ; medullary collecting duct; ; primitive streak; ; neural layer of retina; ; Rostral migratory stream; ; tail of embryo; ; retinal pigment epithelium; ; migratory enteric neural crest cell; ; urothelium; ; embryo;
	More reference expression data
	; ; ; ;
	More reference expression data
Gene ontology
Molecular function	transcription corepressor activity; RNA polymerase II transcription regulatory region sequence-specific DNA binding; chromatin binding; transcription coregulator activity; protein binding; metal ion binding; methylated histone binding; lysine-acetylated histone binding; protein N-terminus binding; zinc ion binding; protein domain specific binding;
Cellular component	cytoplasm; dendritic shaft; dendritic spine; nucleus;
Biological process	regulation of postsynaptic density protein 95 clustering; positive regulation of filopodium assembly; positive regulation of dendritic spine development; positive regulation of dendritic spine maintenance; modulation of excitatory postsynaptic potential; transcription, DNA-templated; regulation of transcription, DNA-templated; negative regulation of cell migration; negative regulation of nucleic acid-templated transcription;
	Sources:Amigo / QuickGO
Orthologs
	23613
	228880
	ENSG00000101040
	ENSMUSG00000039671
	Q9ULU4
	n/a
NM_001281769; NM_001281771; NM_001281772; NM_001281773; NM_001281774;
	NM_001281775; NM_001281776; NM_001281777; NM_001281778; NM_001281779; NM_001281780; NM_001281781; NM_001281782; NM_001281783; NM_001281784; NM_012408; NM_183047; NM_183048; NM_001363714; NM_001363741
NM_001252584; NM_001252585; NM_001252587; NM_001281926; NM_001291158;
	NM_027230; NM_172270; NM_001363018; NM_001363019; NM_001363020; NM_001363021
NP_001268698; NP_001268700; NP_001268701; NP_001268702; NP_001268703;
	NP_001268704; NP_001268705; NP_001268706; NP_001268707; NP_001268708; NP_001268709; NP_001268710; NP_001268711; NP_001268712; NP_001268713; NP_036540; NP_898868; NP_898869; NP_001350643; NP_001350670
	n/a
	Wikidata
View/Edit Human	View/Edit Mouse

Protein kinase C-binding protein 1 is an enzyme that in humans is encoded by the ZMYND8 gene.

The protein encoded by this gene is a receptor for activated C-kinase (RACK) protein. The encoded protein has been shown to bind in vitro to activated protein kinase C beta I. In addition, this protein is a cutaneous T-cell lymphoma-associated antigen. Finally, the protein contains a bromodomain and two zinc fingers, and is thought to be a transcriptional regulator. Multiple transcript variants encoding several different isoforms have been found for this gene.