ZNF366

ZNF366
Identifiers
Aliases	ZNF366, DCSCRIPT, zinc finger protein 366, DC-SCRIPT
External IDs	OMIM: 610159; MGI: 2178429; HomoloGene: 17637; GeneCards: ZNF366; OMA:ZNF366 - orthologs
Gene location (Human)
Chr.	Chromosome 5 (human)
End	72,507,410 bp
Gene location (Mouse)
Chr.	Chromosome 13 (mouse)
End	99,387,164 bp
RNA expression pattern
	Top expressed in
	sural nerve; ; testicle; ; epithelium of colon; ; smooth muscle tissue; ; gonad; ; apex of heart; ; appendix; ; left ventricle; ; lymph node; ; subcutaneous adipose tissue;
	Top expressed in
	lung; ; muscle of thigh; ; quadriceps femoris muscle; ; muscle tissue; ; spleen; ; skeletal muscle tissue; ; white adipose tissue; ; adrenal gland; ; Cerebellum; ; human kidney;
	More reference expression data
	n/a
Gene ontology
Molecular function	DNA binding; estrogen receptor binding; protein binding; transcription corepressor activity; metal ion binding; nucleic acid binding; DNA-binding transcription factor activity, RNA polymerase II-specific;
Cellular component	nucleus;
Biological process	negative regulation of transcription by RNA polymerase II; negative regulation of intracellular estrogen receptor signaling pathway; regulation of transcription, DNA-templated; transcription, DNA-templated; response to estrogen;
	Sources:Amigo / QuickGO
Orthologs
	167465
	238803
	ENSG00000178175
	ENSMUSG00000050919
	Q8N895
	Q6NS86
	NM_152625
	NM_001004149
	NP_689838
	NP_001004149
	Wikidata
View/Edit Human	View/Edit Mouse

Zinc finger protein 366, also known as DC-SCRIPT (Dendritic cell-specific transcript), is a protein that in humans is encoded by the ZNF366 gene. The ZNF366 gene was first identified in a DNA comparison study between 85 kb of Fugu rubripes sequence containing 17 genes with its homologous loci in the human draft genome.