ZRSR2

ZRSR2
Identifiers
Aliases	ZRSR2, U2AF1-RS2, U2AF1L2, U2AF1RS2, URP, ZC3H22, zinc finger CCCH-type, RNA binding motif and serine/arginine rich 2
External IDs	OMIM: 300028; MGI: 103287; HomoloGene: 21061; GeneCards: ZRSR2; OMA:ZRSR2 - orthologs
Gene location (Human)
Chr.	X chromosome (human)
End	15,830,694 bp
Gene location (Mouse)
Chr.	X chromosome (mouse)
End	162,741,657 bp
RNA expression pattern
	Top expressed in
	sural nerve; ; granulocyte; ; monocyte; ; tendon of biceps brachii; ; external globus pallidus; ; tibial arteries; ; spleen; ; gastric mucosa; ; Descending thoracic aorta; ; lymph node;
	Top expressed in
	genital tubercle; ; tail of embryo; ; yolk sac; ; retinal pigment epithelium; ; zygote; ; primitive streak; ; embryo; ; Epithelium of choroid plexus; ; granulocyte; ; muscle of thigh;
	More reference expression data
	; ;
	More reference expression data
Gene ontology
Molecular function	metal ion binding; nucleic acid binding; pre-mRNA 3'-splice site binding; RNA binding; protein binding;
Cellular component	nucleus; spliceosomal complex; U12-type spliceosomal complex; nucleoplasm; U2AF complex;
Biological process	mRNA processing; spliceosomal complex assembly; RNA splicing; mRNA splicing, via spliceosome;
	Sources:Amigo / QuickGO
Orthologs
	8233
	22184
	ENSG00000169249
	ENSMUSG00000031370
	Q15696
	Q62377
	NM_005089
	NM_009453; NM_178794
	NP_005080
	n/a
	Wikidata
View/Edit Human	View/Edit Mouse

U2 small nuclear ribonucleoprotein auxiliary factor 35 kDa subunit-related protein 2 is a protein that in humans is encoded by the ZRSR2 gene.

This gene encodes an essential splicing factor. The encoded protein associates with the U2 auxiliary factor heterodimer, which is required for the recognition of a functional 3' splice site in pre-mRNA splicing, and may play a role in network interactions during spliceosome assembly.