1913 Swiss disease control referendum|
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| Choice | Votes | % |  
| Yes | 169,012 | 60.32% |  
| No | 111,163 | 39.68% |  
| Valid votes | 280,175 | 92.10% |  
| Invalid or blank votes | 24,031 | 7.90% |  
| Total votes | 304,206 | 100.00% |  
| Registered voters/turnout | 844,175 | 36.04% |  | 
A referendum on disease control was held in Switzerland on 4 May 1913. Voters were asked whether they approved of amending two articles of the constitution, 31 II, lit d and 69, which covered the control of human and animal diseases. It was approved by a majority of voters and cantons.