2021–22 Syed Mushtaq Ali Trophy Plate Group
| Dates | 4 – 22 November 2021 | 
|---|---|
| Administrator(s) | BCCI | 
| Cricket format | Twenty20 cricket | 
| Tournament format(s) | Round-robin | 
| Participants | 8 | 
| 2021–22 Indian domestic cricket season | 
|---|
| Men | 
| Women | 
The 2021–22 Syed Mushtaq Ali Trophy was the fourteenth season of the Syed Mushtaq Ali Trophy, a Twenty20 cricket tournament played in India. It was contested by 38 teams, divided into six groups, with eight teams in Plate Group. The tournament was announced by BCCI on 3 July 2021.
On 8 November 2021, in the match between Vidarbha and Manipur, Akshay Karnewar of Vidarbha became the first bowler to bowl four overs in a Twenty20 cricket match without conceding a run. The following day, in Vidarbha's match against Sikkim, Karnewar took a hat-trick. Vidarbha topped the group with five wins out of five to qualify for the preliminary quarter-finals.