2021 São Toméan presidential election|
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| Registered | 123,301 |
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| Turnout | 67.76% (first round) 65.32% (second round) |
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Presidential elections were held in São Tomé and Príncipe on 18 July 2021. As no presidential candidate received a majority of the vote, a second round was originally scheduled to be held on 8 August 2021. However, following an objection to the first-round result, the second round was postponed to 29 August 2021, and later postponed again to 5 September 2021.
The second round was won by Carlos Vila Nova of Independent Democratic Action, who received 58% of the vote, defeating Guilherme Posser da Costa of the MLSTP–PSD. Turnout for the second round was around 65%.