2025 San Luis Open Challenger – Singles

Singles
2025 San Luis Open Challenger
Champion James Duckworth
Runner-up Max Wiskandt
Score6–1, 6–1

Nicolás Mejía was the defending champion but lost in the second round to Santiago Rodríguez Taverna.

James Duckworth won the title after defeating Max Wiskandt 6–1, 6–1 in the final.