2025 San Luis Open Challenger – Singles
| Singles | |
|---|---|
| 2025 San Luis Open Challenger | |
| Champion | James Duckworth |
| Runner-up | Max Wiskandt |
| Score | 6–1, 6–1 |
Nicolás Mejía was the defending champion but lost in the second round to Santiago Rodríguez Taverna.
James Duckworth won the title after defeating Max Wiskandt 6–1, 6–1 in the final.