AMP deaminase

AMPD1
Identifiers
Aliases	AMPD1, MAD, MADA, MMDD, adenosine monophosphate deaminase 1, AMP deaminase, AMPD
External IDs	OMIM: 102770; MGI: 88015; HomoloGene: 20; GeneCards: AMPD1; OMA:AMPD1 - orthologs
Gene location (Human)
Chr.	Chromosome 1 (human)
End	114,695,618 bp
Gene location (Mouse)
Chr.	Chromosome 3 (mouse)
End	103,007,036 bp
RNA expression pattern
	Top expressed in
	triceps brachii muscle; ; vastus lateralis muscle; ; Skeletal muscle tissue of rectus abdominis; ; biceps brachii; ; glutes; ; Skeletal muscle tissue of biceps brachii; ; muscle of thigh; ; thoracic diaphragm; ; deltoid muscle; ; gastrocnemius muscle;
	Top expressed in
	quadriceps femoris muscle; ; muscle of thigh; ; skeletal muscle tissue; ; zone of skin; ; esophagus; ; lip; ; thymus; ; embryo; ; zygote; ; blastocyst;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	hydrolase activity; myosin heavy chain binding; metal ion binding; deaminase activity; AMP deaminase activity;
Cellular component	cytosol;
Biological process	response to organic substance; IMP salvage; nucleotide metabolic process; purine-containing compound salvage; purine ribonucleoside monophosphate biosynthetic process; IMP biosynthetic process; AMP metabolic process;
	Sources:Amigo / QuickGO
Orthologs
	270
	229665
	ENSG00000116748
	ENSMUSG00000070385
	P23109
	Q3V1D3
	NM_001172626; NM_000036
	NM_001033303
	NP_000027; NP_001166097
	NP_001028475
	Wikidata
View/Edit Human	View/Edit Mouse

AMP deaminase 1 is an enzyme that in humans is encoded by the AMPD1 gene.

Adenosine monophosphate deaminase is an enzyme that converts adenosine monophosphate (AMP) to inosine monophosphate (IMP), freeing an ammonia molecule in the process.