APLP2

APLP2
Identifiers
Aliases	APLP2, APLP-2, APPH, APPL2, CDEBP, amyloid beta precursor like protein 2
External IDs	OMIM: 104776; MGI: 88047; HomoloGene: 20396; GeneCards: APLP2; OMA:APLP2 - orthologs
Gene location (Human)
Chr.	Chromosome 11 (human)
End	130,144,811 bp
Gene location (Mouse)
Chr.	Chromosome 9 (mouse)
End	31,123,111 bp
RNA expression pattern
	Top expressed in
	renal medulla; ; Epithelium of choroid plexus; ; trigeminal ganglion; ; internal globus pallidus; ; monocyte; ; lower lobe of lung; ; Descending thoracic aorta; ; synovial joint; ; spinal ganglia; ; left lobe of thyroid gland;
	Top expressed in
	neural layer of retina; ; ciliary body; ; cerebellar cortex; ; cerebellar vermis; ; medial dorsal nucleus; ; lobe of cerebellum; ; lateral geniculate nucleus; ; medial geniculate nucleus; ; olfactory epithelium; ; white adipose tissue;
	More reference expression data
	; ; ; ;
	More reference expression data
Gene ontology
Molecular function	peptidase inhibitor activity; DNA binding; transition metal ion binding; heparin binding; protein binding; serine-type endopeptidase inhibitor activity; identical protein binding; metal ion binding;
Cellular component	integral component of membrane; extracellular exosome; membrane; nucleus; platelet alpha granule membrane; plasma membrane; endoplasmic reticulum lumen;
Biological process	G protein-coupled receptor signaling pathway; negative regulation of peptidase activity; negative regulation of endopeptidase activity; platelet degranulation; post-translational protein modification;
	Sources:Amigo / QuickGO
Orthologs
	334
	11804
	ENSG00000084234
	ENSMUSG00000031996
	Q06481
	Q06335
NM_001142276; NM_001142277; NM_001142278; NM_001243299; NM_001642;
	NM_001328682; NM_001328684; NM_001328685; NM_001328686
	NM_001102455; NM_001102456; NM_009691; NM_001357698
NP_001135748; NP_001135749; NP_001135750; NP_001230228; NP_001315611;
	NP_001315613; NP_001315614; NP_001315615; NP_001633; NP_001369455; NP_001369456; NP_001369457; NP_001369458; NP_001369459; NP_001369460; NP_001369461; NP_001369462; NP_001369463; NP_001369464; NP_001369465; NP_001369466; NP_001369467; NP_001369468; NP_001369469; NP_001369470; NP_001369471; NP_001369472; NP_001369473; NP_001369474; NP_001369475
	NP_001095925; NP_001095926; NP_033821; NP_001344627
	Wikidata
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Amyloid precursor like protein 2, also known as APLP2, is a protein encoded by the APLP2 gene in humans. APLP2 along with APLP1 are important modulators of glucose and insulin homeostasis.