ATG9A

ATG9A
Identifiers
Aliases	ATG9A, APG9L1, MGD3208, mATG9, autophagy related 9A
External IDs	OMIM: 612204; MGI: 2138446; HomoloGene: 34495; GeneCards: ATG9A; OMA:ATG9A - orthologs
Gene location (Human)
Chr.	Chromosome 2 (human)
End	219,229,717 bp
Gene location (Mouse)
Chr.	Chromosome 1 (mouse)
End	75,168,840 bp
RNA expression pattern
	Top expressed in
	gastrocnemius muscle; ; skeletal muscle tissue; ; apex of heart; ; muscle of thigh; ; left testis; ; right testis; ; blood; ; stromal cell of endometrium; ; left ventricle; ; prefrontal cortex;
	Top expressed in
	muscle of thigh; ; testicle; ; skeletal muscle tissue; ; quadriceps femoris muscle; ; spermatid; ; granulocyte; ; striatum of neuraxis; ; superior frontal gyrus; ; primary visual cortex; ; cerebellar cortex;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	protein binding;
Cellular component	integral component of membrane; recycling endosome; endosome; late endosome; Golgi apparatus; endoplasmic reticulum membrane; membrane; late endosome membrane; phagophore assembly site; trans-Golgi network; autophagosome membrane; endoplasmic reticulum; cytoplasmic vesicle; autophagosome; intracellular membrane-bounded organelle; cytoplasmic vesicle membrane;
Biological process	protein localization to phagophore assembly site; autophagosome assembly; autophagy; autophagy of mitochondrion; late nucleophagy; protein transport; response to nutrient levels; transport;
	Sources:Amigo / QuickGO
Orthologs
	79065
	245860
	ENSG00000198925
	ENSMUSG00000033124
	Q7Z3C6
	Q68FE2
	NM_001077198; NM_024085
	NM_001003917; NM_001288612; NM_001288613
	NP_001070666; NP_076990; NP_001070666.1; NP_076990.4
NP_001003917; NP_001275541; NP_001275542; NP_001395154; NP_001395156;
	NP_001395158; NP_001395159; NP_001395160
	Wikidata
View/Edit Human	View/Edit Mouse

Autophagy-related protein 9A is a protein that in humans is encoded by the ATG9A gene.

Functional studies indicate that ATG9A plays a role in autophagy. and other non-autophagy membrane remodeling processes such as plasma membrane repair. Enzymatically, it is a lipid scramblase. ATG9A interacts with IQGAP1 and the ESCRT machinery in membrane remodeling.