Anhalonidine

Anhalonidine
Names
IUPAC name
(1S)-1,2,3,4-Tetrahydro-6,7-dimethoxy-1-methyl-8-isoquinolinol
Other names
N-Desmethylpellotine
Identifiers
3D model (JSmol)
ChemSpider
KEGG
UNII
  • InChI=1S/C12H17NO3/c1-7-10-8(4-5-13-7)6-9(15-2)12(16-3)11(10)14/h6-7,13-14H,4-5H2,1-3H3/t7-/m0/s1
    Key: PRNZAMQMBOFSJY-ZETCQYMHSA-N
  • InChI=1/C12H17NO3/c1-7-10-8(4-5-13-7)6-9(15-2)12(16-3)11(10)14/h6-7,13-14H,4-5H2,1-3H3/t7-/m0/s1
    Key: PRNZAMQMBOFSJY-ZETCQYMHBW
  • C[C@H]1c2c(cc(c(c2O)OC)OC)CCN1
Properties
C12H17NO3
Molar mass 223.272 g·mol−1
Melting point 160 °C (320 °F; 433 K)
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
Infobox references

Anhalonidine, also known as N-desmethylpellotine, a naturally occurring tetrahydroisoquinoline alkaloid which can be isolated from certain members of the cactus family, such as Lophophora. It is structurally related to mescaline. Anhalonidine produced no hallucinogenic effects in humans at doses of up to 250 mg. However, it has been reported to have a calming or sedative effect instead, with about one-fourth the potency of pellotine and with marked sedation occurring at doses of 100 to 250 mg. Anhalonidine has been found to act as a potent inverse agonist of the serotonin 5-HT7 receptor.