Autophagy-related protein 13

ATG13
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	5C50
Identifiers
Aliases	ATG13, KIAA0652, PARATARG8, autophagy related 13
External IDs	OMIM: 615088; MGI: 1196429; HomoloGene: 32229; GeneCards: ATG13; OMA:ATG13 - orthologs
Gene location (Human)
Chr.	Chromosome 11 (human)
End	46,674,818 bp
Gene location (Mouse)
Chr.	Chromosome 2 (mouse)
End	91,540,921 bp
RNA expression pattern
	Top expressed in
	left testis; ; right testis; ; anterior pituitary; ; epithelium of colon; ; prefrontal cortex; ; right frontal lobe; ; skin of leg; ; tibial nerve; ; right hemisphere of cerebellum; ; body of pancreas;
	Top expressed in
	neural layer of retina; ; superior frontal gyrus; ; muscle of thigh; ; dentate gyrus of hippocampal formation granule cell; ; primary visual cortex; ; lip; ; blastocyst; ; cerebellar cortex; ; epithelium of lens; ; esophagus;
	More reference expression data
	n/a
Gene ontology
Molecular function	protein binding; protein kinase binding;
Cellular component	cytoplasm; cytosol; Atg1/ULK1 kinase complex; mitochondrion; phagophore assembly site; endoplasmic reticulum membrane;
Biological process	autophagy; macroautophagy; autophagosome assembly; positive regulation of protein targeting to mitochondrion; mitophagy; response to mitochondrial depolarisation; regulation of macroautophagy;
	Sources:Amigo / QuickGO
Orthologs
	9776
	51897
	ENSG00000175224
	ENSMUSG00000027244
	O75143
	Q91YI1
NM_001142673; NM_001205119; NM_001205120; NM_001205121; NM_001205122;
	NM_001346311; NM_001346312; NM_001346313; NM_001346314; NM_001346315; NM_001346316; NM_001346317; NM_001346318; NM_001346319; NM_001346320; NM_001346321; NM_001346322; NM_001346323; NM_001346324; NM_001346325; NM_001346326; NM_001346327; NM_001346328; NM_001346329; NM_001346330; NM_001346331; NM_001346332; NM_001346333; NM_001346334; NM_001346335; NM_001346336; NM_001346337; NM_001346338; NM_001346340; NM_001346342; NM_001346344; NM_001346346; NM_001346348; NM_001346349; NM_001346350; NM_001346351; NM_001346352; NM_001346353; NM_001346354; NM_001346355; NM_001346356; NM_001346357; NM_001346358; NM_001346359; NM_001346360; NM_014741
NM_145528; NM_001355416; NM_001355417; NM_001355418; NM_001355419;
	NM_001355420; NM_001355421
NP_001136145; NP_001192048; NP_001192049; NP_001192050; NP_001192051;
	NP_001333240; NP_001333241; NP_001333242; NP_001333243; NP_001333244; NP_001333245; NP_001333246; NP_001333247; NP_001333248; NP_001333249; NP_001333250; NP_001333251; NP_001333252; NP_001333253; NP_001333254; NP_001333255; NP_001333256; NP_001333257; NP_001333258; NP_001333259; NP_001333260; NP_001333261; NP_001333262; NP_001333263; NP_001333264; NP_001333265; NP_001333266; NP_001333267; NP_001333269; NP_001333271; NP_001333273; NP_001333275; NP_001333277; NP_001333278; NP_001333279; NP_001333280; NP_001333281; NP_001333282; NP_001333283; NP_001333284; NP_001333285; NP_001333286; NP_001333287; NP_001333288; NP_001333289; NP_055556
NP_663503; NP_001342345; NP_001342346; NP_001342347; NP_001342348;
	NP_001342349; NP_001342350
	Wikidata
View/Edit Human	View/Edit Mouse

Autophagy-related protein 13 also known as ATG13 is a protein that in humans is encoded by the KIAA0652 gene.

ATG13 is an autophagy factor required for phagosome formation. ATG13 is a target of the TOR kinase signaling pathway that regulates autophagy through phosphorylation of ATG13 and ULK1, and the regulation of the ATG13-ULK1-RB1CC1 complex.