CEP135

CEP135
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	5FCN
Identifiers
Aliases	CEP135, CEP4, KIAA0635, MCPH8, centrosomal protein 135
External IDs	OMIM: 611423; MGI: 2681869; HomoloGene: 45709; GeneCards: CEP135; OMA:CEP135 - orthologs
Gene location (Human)
Chr.	Chromosome 4 (human)
End	56,033,361 bp
Gene location (Mouse)
Chr.	Chromosome 5 (mouse)
End	76,794,313 bp
RNA expression pattern
	Top expressed in
	amniotic fluid; ; buccal mucosa cell; ; sperm; ; ventricular zone; ; testicle; ; gonad; ; bone marrow; ; monocyte; ; Achilles tendon; ; secondary oocyte;
	Top expressed in
	zygote; ; genital tubercle; ; tail of embryo; ; secondary oocyte; ; spermatid; ; spermatocyte; ; granulocyte; ; ventricular zone; ; primary oocyte; ; epiblast;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	protein C-terminus binding; protein binding;
Cellular component	cytoplasm; centriole; cytosol; centrosome; cytoskeleton;
Biological process	centriole replication; centriole-centriole cohesion; G2/M transition of mitotic cell cycle; positive regulation of non-motile cilium assembly; ciliary basal body-plasma membrane docking; regulation of G2/M transition of mitotic cell cycle; positive regulation of establishment of protein localization;
	Sources:Amigo / QuickGO
Orthologs
	9662
	381644
	ENSG00000174799
	ENSMUSG00000036403
	Q66GS9
	Q6P5D4
	NM_014645; NM_025009
	NM_199032
	NP_079285
	NP_950197
	Wikidata
View/Edit Human	View/Edit Mouse

Centrosomal protein of 135 kDa is a protein that in humans is encoded by the CEP135 gene. It is part of the centrosome throughout the cell cycle, being distributed in the pericentriolar material. CEP135 is required for the centriolar localization of CEP250.