DEPDC1B

DEPDC1B
Identifiers
Aliases	DEPDC1B, BRCC3, XTP1, DEP domain containing 1B
External IDs	OMIM: 616073; MGI: 2145425; HomoloGene: 10157; GeneCards: DEPDC1B; OMA:DEPDC1B - orthologs
Gene location (Human)
Chr.	Chromosome 5 (human)
End	60,700,190 bp
Gene location (Mouse)
Chr.	Chromosome 13 (mouse)
End	108,544,316 bp
RNA expression pattern
	Top expressed in
	secondary oocyte; ; ventricular zone; ; gallbladder; ; ganglionic eminence; ; gonad; ; placenta; ; thymus; ; testicle; ; bone marrow; ; bone marrow cells;
	Top expressed in
	hand; ; granulocyte; ; right kidney; ; medial ganglionic eminence; ; maxillary prominence; ; primitive streak; ; mandibular prominence; ; spermatocyte; ; endocardial cushion; ; epiblast;
	More reference expression data
	n/a
Gene ontology
Molecular function	GTPase activator activity;
Cellular component	cytosol;
Biological process	positive regulation of Wnt signaling pathway; positive regulation of GTPase activity; intracellular signal transduction; regulation of small GTPase mediated signal transduction; cell migration; signal transduction;
	Sources:Amigo / QuickGO
Orthologs
	55789
	218581
	ENSG00000035499
	ENSMUSG00000021697
	Q8WUY9
	Q8BH88
	NM_001145208; NM_018369
	NM_178683
	NP_001138680; NP_060839
	NP_848798
	Wikidata
View/Edit Human	View/Edit Mouse

DEP Domain Containing Protein 1B also known as XTP1, XTP8, HBV XAg-Transactivated Protein 8, formerly referred to as BRCC3 is a human protein encoded by a gene of similar name located on chromosome 5.

The precise function of DEPDC1B is currently unknown. Expression profiles indicate that DEPDC1B is highly expressed ubiquitously throughout human tissue.