DNAJC19

DNAJC19
Identifiers
AliasesDNAJC19, PAM18, TIM14, TIMM14, DnaJ heat shock protein family (Hsp40) member C19
External IDsOMIM: 608977; MGI: 3709029; HomoloGene: 87176; GeneCards: DNAJC19; OMA:DNAJC19 - orthologs
Orthologs
SpeciesHumanMouse
Entrez

131118

100503724

Ensembl

ENSG00000205981

ENSMUSG00000083854

UniProt

Q96DA6

Q9CQV7

RefSeq (mRNA)

NM_001190233
NM_145261
NM_201259
NM_201260
NM_201261

XM_003084719

RefSeq (protein)

NP_001177162
NP_660304

NP_001021382
NP_001273901
NP_001273902
NP_080608

Location (UCSC)Chr 3: 180.98 – 180.99 Mbn/a
PubMed search
Wikidata
View/Edit HumanView/Edit Mouse

Mitochondrial import inner membrane translocase subunit TIM14 is an enzyme that in humans is encoded by the DNAJC19 gene on chromosome 3. TIM14 belongs to the DnaJ family, which has been involved in Hsp40/Hsp70 chaperone systems. As a mitochondrial chaperone, TIM14 functions as part of the TIM23 complex import motor to facilitate the import of nuclear-encoded proteins into the mitochondria. TIM14 also complexes with prohibitin complexes to regulate mitochondrial morphogenesis, and has been implicated in dilated cardiomyopathy with ataxia.