Diaminohydroxyphosphoribosylaminopyrimidine deaminase
| diaminohydroxyphosphoribosylaminopyrimidine deaminase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC no. | 3.5.4.26 | ||||||||
| CAS no. | 68994-19-4 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| Gene Ontology | AmiGO / QuickGO | ||||||||
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In enzymology, a diaminohydroxyphosphoribosylaminopyrimidine deaminase (EC 3.5.4.26) is an enzyme that catalyzes the chemical reaction
- 2,5-diamino-6-hydroxy-4-(5-phosphoribosylamino)pyrimidine + H2O 5-amino-6-(5-phosphoribosylamino)uracil + NH3
Thus, the two substrates of this enzyme are 2,5-diamino-6-hydroxy-4-(5-phosphoribosylamino)pyrimidine and H2O, whereas its two products are 5-amino-6-(5-phosphoribosylamino)uracil and NH3.
This enzyme belongs to the family of hydrolases, those acting on carbon-nitrogen bonds other than peptide bonds (specifically in cyclic amidines). The systematic name of this enzyme class is 2,5-diamino-6-hydroxy-4-(5-phosphoribosylamino)pyrimidine 2-aminohydrolase. This enzyme participates in riboflavin metabolism.