EPS8L1

EPS8L1
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	2K2M, 2ROL
Identifiers
Aliases	EPS8L1, DRC3, EPS8R1, PP10566, EPS8 like 1
External IDs	OMIM: 614987; MGI: 1914675; HomoloGene: 15767; GeneCards: EPS8L1; OMA:EPS8L1 - orthologs
Gene location (Human)
Chr.	Chromosome 19 (human)
End	55,087,923 bp
Gene location (Mouse)
Chr.	Chromosome 7 (mouse)
End	4,483,486 bp
RNA expression pattern
	Top expressed in
	right uterine tube; ; buccal mucosa cell; ; skin of abdomen; ; skin of leg; ; amniotic fluid; ; right lobe of thyroid gland; ; left lobe of thyroid gland; ; pancreatic ductal cell; ; oral cavity; ; minor salivary glands;
	Top expressed in
	esophagus; ; lip; ; skin of external ear; ; granulocyte; ; conjunctival fornix; ; skin of back; ; neural layer of retina; ; left lung lobe; ; right lung lobe; ; cornea;
	More reference expression data
	; ; ; ;
	More reference expression data
Gene ontology
Molecular function	actin binding; T cell receptor binding; protein binding; cadherin binding;
Cellular component	ruffle membrane; extracellular exosome; cytoplasm; cytosol; plasma membrane; protein-containing complex;
Biological process	regulation of Rho protein signal transduction; Rho protein signal transduction; positive regulation of ruffle assembly; regulation of molecular function;
	Sources:Amigo / QuickGO
Orthologs
	54869
	67425
	ENSG00000131037
	ENSMUSG00000006154
	Q8TE68
	Q8R5F8
	NM_017729; NM_133180; NM_139204
	NM_001290416; NM_026146; NM_001374622
	NP_060199; NP_573441
	NP_001277345; NP_080422; NP_001361551
	Wikidata
View/Edit Human	View/Edit Mouse

Epidermal growth factor receptor kinase substrate 8-like protein 1 is an enzyme that in humans is encoded by the EPS8L1 gene.

This gene encodes a protein that is related to epidermal growth factor receptor pathway substrate 8 (EPS8), a substrate for the epidermal growth factor receptor. The function of this protein is unknown. Several alternatively spliced transcript variants encoding different isoforms exist.