EPS8L2

EPS8L2
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	1WWU, 1WXB
Identifiers
Aliases	EPS8L2, EPS8R2, EPS8 like 2, DFNB106
External IDs	OMIM: 614988; MGI: 2138828; HomoloGene: 69358; GeneCards: EPS8L2; OMA:EPS8L2 - orthologs
Gene location (Human)
Chr.	Chromosome 11 (human)
End	727,727 bp
Gene location (Mouse)
Chr.	Chromosome 7 (mouse)
End	140,942,933 bp
RNA expression pattern
	Top expressed in
	left lobe of thyroid gland; ; right lobe of thyroid gland; ; minor salivary glands; ; right lobe of liver; ; right uterine tube; ; mucosa of transverse colon; ; skin of abdomen; ; skin of leg; ; amniotic fluid; ; olfactory zone of nasal mucosa;
	Top expressed in
	intestinal villus; ; esophagus; ; right kidney; ; lip; ; epithelium of small intestine; ; duodenum; ; yolk sac; ; ileum; ; jejunum; ; pyloric antrum;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	actin binding; cadherin binding; protein binding;
Cellular component	ruffle membrane; vesicle; plasma membrane; extracellular exosome; cytoplasm; cytosol; stereocilium bundle; stereocilium tip; stereocilium; protein-containing complex; cell projection;
Biological process	regulation of Rho protein signal transduction; Rho protein signal transduction; positive regulation of ruffle assembly; hearing; regulation of molecular function;
	Sources:Amigo / QuickGO
Orthologs
	64787
	98845
	ENSG00000177106
	ENSMUSG00000025504
	Q9H6S3
	Q99K30
	NM_022772
	NM_133191
	NP_073609
	NP_573454
	Wikidata
View/Edit Human	View/Edit Mouse

Epidermal growth factor receptor kinase substrate 8-like protein 2 is an enzyme that in humans is encoded by the EPS8L2 gene.

This gene encodes a protein that is related to epidermal growth factor receptor pathway substrate 8 (EPS8), a substrate for the epidermal growth factor receptor. The function of this protein is unknown.