EPS8L3

EPS8L3
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	1WXT
Identifiers
Aliases	EPS8L3, EPS8R3, EPS8 like 3, HYPT5
External IDs	OMIM: 614989; MGI: 2139743; HomoloGene: 15878; GeneCards: EPS8L3; OMA:EPS8L3 - orthologs
Gene location (Human)
Chr.	Chromosome 1 (human)
End	109,764,027 bp
Gene location (Mouse)
Chr.	Chromosome 3 (mouse)
End	107,800,216 bp
RNA expression pattern
	Top expressed in
	mucosa of transverse colon; ; rectum; ; mucosa of ileum; ; gallbladder; ; jejunal mucosa; ; duodenum; ; mucosa of sigmoid colon; ; gastric mucosa; ; pancreatic ductal cell; ; testicle;
	Top expressed in
	intestinal villus; ; ileum; ; duodenum; ; epithelium of small intestine; ; large intestine; ; colon; ; jejunum; ; left colon; ; crypt of lieberkuhn of small intestine; ; zygote;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	protein binding; actin filament binding; actin binding;
Cellular component	cytoplasm; plasma membrane; ruffle membrane;
Biological process	regulation of hair cycle; Rho protein signal transduction; regulation of Rho protein signal transduction; positive regulation of ruffle assembly;
	Sources:Amigo / QuickGO
Orthologs
	79574
	99662
	ENSG00000198758
	ENSMUSG00000040600
	Q8TE67
	Q91WL0
	NM_024526; NM_133181; NM_139053; NM_001319952
	NM_133867
	NP_001306881; NP_078802; NP_573444; NP_620641
	NP_598628
	Wikidata
View/Edit Human	View/Edit Mouse

Epidermal growth factor receptor kinase substrate 8-like protein 3 is an enzyme that in humans is encoded by the EPS8L3 gene.

This gene encodes a protein that is related to epidermal growth factor receptor pathway substrate 8 (EPS8), a substrate for the epidermal growth factor receptor. The function of this protein is unknown. Alternatively spliced transcript variants encoding different isoforms exist.