GLB1

GLB1
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	3THC, 3THD, 3WEZ, 3WF0, 3WF1, 3WF2, 3WF3, 3WF4
Identifiers
Aliases	GLB1, EBP, ELNR1, MPS4B, galactosidase beta 1
External IDs	OMIM: 611458; MGI: 88151; HomoloGene: 47922; GeneCards: GLB1; OMA:GLB1 - orthologs
Gene location (Human)
Chr.	Chromosome 3 (human)
End	33,097,202 bp
Gene location (Mouse)
Chr.	Chromosome 9 (mouse)
End	114,303,966 bp
RNA expression pattern
	Top expressed in
	monocyte; ; stromal cell of endometrium; ; secondary oocyte; ; islet of Langerhans; ; corpus epididymis; ; granulocyte; ; rectum; ; epithelium of colon; ; gallbladder; ; tibia;
	Top expressed in
	right kidney; ; human kidney; ; proximal tubule; ; migratory enteric neural crest cell; ; seminal vesicula; ; epithelium of small intestine; ; blastocyst; ; stroma of bone marrow; ; calvaria; ; yolk sac;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	protein binding; hydrolase activity, hydrolyzing O-glycosyl compounds; galactoside binding; hydrolase activity, acting on glycosyl bonds; hydrolase activity; exo-alpha-sialidase activity; beta-galactosidase activity; protein homodimerization activity;
Cellular component	perinuclear region of cytoplasm; Golgi apparatus; lysosome; lysosomal lumen; intracellular membrane-bounded organelle; extracellular exosome; cytoplasm; vacuole; extracellular region; extracellular space; azurophil granule lumen; ficolin-1-rich granule lumen;
Biological process	galactose catabolic process; glycosphingolipid metabolic process; cellular carbohydrate metabolic process; keratan sulfate catabolic process; metabolism; glycosaminoglycan catabolic process; neutrophil degranulation; response to cortisone; response to Thyroglobulin triiodothyronine; carbohydrate metabolic process;
	Sources:Amigo / QuickGO
Orthologs
	2720
	12091
	ENSG00000170266
	ENSMUSG00000045594
	P16278
	P23780
	NM_001135602; NM_000404; NM_001079811; NM_001317040; NM_001393580
	NM_009752
	NP_000395; NP_001073279; NP_001129074; NP_001303969
	NP_033882
	Wikidata
View/Edit Human	View/Edit Mouse

Galactosidase, beta 1, also known as GLB1, is a protein which in humans is encoded by the GLB1 gene.

The GLB1 protein is a beta-galactosidase that cleaves the terminal beta-galactose from ganglioside substrates and other glycoconjugates. The GLB1 gene also encodes an elastin binding protein.

In corn (Zea mays), Glb1 is a gene coding for the storage protein globulin.