Estropipate

Estropipate
Clinical data
Trade names	Harmogen, Improvera, Ogen, Ortho-Est, Sulestrex, others
Other names	Piperazine estrone sulfate; Estrone sulfate piperazine salt; Pipestrone
AHFS/Drugs.com	Monograph
Routes of; administration	By mouth
Drug class	Estrogen; Estrogen ester
ATC code	None;
Identifiers
	IUPAC name [(8R,9S,13S,14S)-13-Methyl-17-oxo-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthren-3-yl] hydrogen sulfate; piperazine;
CAS Number	7280-37-7 ;
PubChem CID	5284555;
DrugBank	DB04574 ;
ChemSpider	4447610 ;
UNII	SVI38UY019;
KEGG	D00948 ;
ChEBI	CHEBI:4873 ;
ChEMBL	ChEMBL1200980 ;
CompTox Dashboard (EPA)	DTXSID3023005 ;
ECHA InfoCard	100.027.906
Chemical and physical data
Formula	C22H32N2O5S
Molar mass	436.57 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES O=S(=O)(O)Oc1cc4c(cc1)[C@@H]3[C@H]([C@@H]2CCC(=O)[C@@]2(C)CC3)CC4.N1CCNCC1;
	InChI InChI=1S/C18H22O5S.C4H10N2/c1-18-9-8-14-13-5-3-12(23-24(20,21)22)10-11(13)2-4-15(14)16(18)6-7-17(18)19;1-2-6-4-3-5-1/h3,5,10,14-16H,2,4,6-9H2,1H3,(H,20,21,22);5-6H,1-4H2/t14-,15-,16+,18+;/m1./s1 ; Key:HZEQBCVBILBTEP-ZFINNJDLSA-N ;
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Estropipate, also known as piperazine estrone sulfate and sold under the brand names Harmogen, Improvera, Ogen, Ortho-Est, and Sulestrex among others, is an estrogen medication which is used mainly in menopausal hormone therapy in the treatment of menopausal symptoms. It is a salt of estrone sulfate and piperazine, and is transformed into estrone and estradiol in the body. It is taken by mouth.