GNA11

GNA11
Identifiers
Aliases	GNA11, FBH, FBH2, FHH2, GNA-11, HHC2, HYPOC2, G protein subunit alpha 11, HG1K
External IDs	OMIM: 139313; MGI: 95766; HomoloGene: 20474; GeneCards: GNA11; OMA:GNA11 - orthologs
Gene location (Human)
Chr.	Chromosome 19 (human)
End	3,123,999 bp
Gene location (Mouse)
Chr.	Chromosome 10 (mouse)
End	81,381,024 bp
RNA expression pattern
	Top expressed in
	mucosa of ileum; ; jejunal mucosa; ; pancreatic ductal cell; ; duodenum; ; mucosa of transverse colon; ; secondary oocyte; ; cerebellar vermis; ; parotid gland; ; right hemisphere of cerebellum; ; stromal cell of endometrium;
	Top expressed in
	crypt of lieberkuhn of small intestine; ; duodenum; ; jejunum; ; ileum; ; intestinal villus; ; migratory enteric neural crest cell; ; epithelium of small intestine; ; left colon; ; Ileal epithelium; ; Paneth cell;
	More reference expression data
	; ; ; ;
	More reference expression data
Gene ontology
Molecular function	nucleotide binding; type 2A serotonin receptor binding; GTP binding; metal ion binding; guanyl nucleotide binding; G protein-coupled receptor binding; GTPase activity; signal transducer activity; G-protein beta/gamma-subunit complex binding; protein binding;
Cellular component	cytoplasm; membrane; plasma membrane; photoreceptor outer segment; lysosomal membrane; extracellular exosome; heterotrimeric G-protein complex;
Biological process	G protein-coupled acetylcholine receptor signaling pathway; skeletal system development; regulation of melanocyte differentiation; entrainment of circadian clock; platelet activation; heart development; cellular response to pH; phospholipase C-activating dopamine receptor signaling pathway; phototransduction, visible light; developmental pigmentation; action potential; signal transduction; adenylate cyclase-modulating G protein-coupled receptor signaling pathway; G protein-coupled receptor signaling pathway;
	Sources:Amigo / QuickGO
Orthologs
	2767
	14672
	ENSG00000088256
	ENSMUSG00000034781
	P29992
	P21278
	NM_002067
	NM_010301
	NP_002058
	NP_034431
	Wikidata
View/Edit Human	View/Edit Mouse

Guanine nucleotide-binding protein subunit alpha-11 is a protein that in humans is encoded by the GNA11 gene. Together with GNAQ (its paralogue), it functions as a Gq alpha subunit.