GNA15

GNA15
Identifiers
Aliases	GNA15, GNA16, G protein subunit alpha 15, HG1L
External IDs	OMIM: 139314; MGI: 95770; HomoloGene: 1563; GeneCards: GNA15; OMA:GNA15 - orthologs
Gene location (Human)
Chr.	Chromosome 19 (human)
End	3,163,749 bp
Gene location (Mouse)
Chr.	Chromosome 10 (mouse)
End	81,360,059 bp
RNA expression pattern
	Top expressed in
	palpebral conjunctiva; ; gingival epithelium; ; monocyte; ; oral cavity; ; skin of abdomen; ; buccal mucosa cell; ; amniotic fluid; ; skin of leg; ; olfactory zone of nasal mucosa; ; periodontal fiber;
	Top expressed in
	granulocyte; ; lip; ; esophagus; ; embryo; ; transitional epithelium of urinary bladder; ; embryo; ; morula; ; blastocyst; ; zone of skin; ; stroma of bone marrow;
	More reference expression data
	n/a
Gene ontology
Molecular function	guanyl nucleotide binding; nucleotide binding; GTP binding; metal ion binding; GTPase activity; G-protein beta/gamma-subunit complex binding; G protein-coupled receptor binding; signal transducer activity;
Cellular component	plasma membrane; heterotrimeric G-protein complex;
Biological process	platelet activation; phospholipase C-activating G protein-coupled receptor signaling pathway; phospholipase C-activating G protein-coupled acetylcholine receptor signaling pathway; phospholipase C-activating dopamine receptor signaling pathway; activation of phospholipase C activity; signal transduction; adenylate cyclase-modulating G protein-coupled receptor signaling pathway; G protein-coupled receptor signaling pathway; positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G protein-coupled signaling pathway;
	Sources:Amigo / QuickGO
Orthologs
	2769
	14676
	ENSG00000060558
	ENSMUSG00000034792
	P30679
	P30678
	NM_002068
	NM_010304
	NP_002059
	NP_034434
	Wikidata
View/Edit Human	View/Edit Mouse

Guanine nucleotide-binding protein subunit alpha-15 is a protein that in humans is encoded by the GNA15 gene. G₁₅α is a member of the Gq alpha subunit family, and functions as a constituent of a heterotrimeric G protein in cell signal transduction. It was also previously known as G₁₆α.