GNGT1

GNGT1
Identifiers
Aliases	GNGT1, GNG1, G protein subunit gamma transducin 1, HG3G1
External IDs	OMIM: 189970; MGI: 109165; HomoloGene: 7738; GeneCards: GNGT1; OMA:GNGT1 - orthologs
Gene location (Human)
Chr.	Chromosome 7 (human)
End	93,911,265 bp
Gene location (Mouse)
Chr.	Chromosome 6 (mouse)
End	3,997,436 bp
RNA expression pattern
	Top expressed in
	retinal pigment epithelium; ; buccal mucosa cell; ; testicle; ; gonad; ; placenta; ; paraflocculus of cerebellum; ; amniotic fluid; ; Epithelium of choroid plexus; ; monocyte; ; thymus;
	Top expressed in
	neural layer of retina; ; retinal pigment epithelium; ; epithelium of lens; ; pineal gland; ; lumbar subsegment of spinal cord; ; lumbar spinal ganglion; ; ciliary body; ; iris; ; internal carotid artery; ; external carotid artery;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	protein binding; signal transducer activity; GTPase activity; G-protein beta-subunit binding;
Cellular component	photoreceptor inner segment; membrane; photoreceptor outer segment; photoreceptor disc membrane; heterotrimeric G-protein complex; plasma membrane; G-protein beta/gamma-subunit complex;
Biological process	phototransduction; protein localization; cardiac muscle cell apoptotic process; cellular response to hypoxia; rhodopsin mediated signaling pathway; eye photoreceptor cell development; signal transduction; G protein-coupled receptor signaling pathway;
	Sources:Amigo / QuickGO
Orthologs
	2792
	14699
	ENSG00000127928
	ENSMUSG00000029663
	P63211
	Q61012
	NM_021955; NM_001329426
	NM_010314
	NP_001316355; NP_068774
	NP_034444
	Wikidata
View/Edit Human	View/Edit Mouse

Guanine nucleotide-binding protein G(T) subunit gamma-T1 is a protein that in humans is encoded by the GNGT1 gene. Either GNGT1 or GNGT2 is the gamma subunit (G_γ) of the G_βγ part of transducin (written G(T) or G_t), a heterotrimeric G-protein naturally expressed in vertebrate retina rod and cone cells. GNGT1 only occurs in rod cells, and GNGT2 only occurs in cone cells, with a different alpha (G_α) subunit.